Itandehui Jansen studied film directing at the Netherlands Film Academy in Amsterdam. She participated in the Berlinale Talents and the Binger Film Screenwriting Lab. Her films have screened at various international film festivals, such as the International Documentary Film Festival Amsterdam (IDFA), The Cork International Film Festival and the Morelia International Film Festival. Her short film The Last Council received several international awards and was nominated to the Mexican Film Critics Award Diosa de Plata. In 2015 she received her PhD from the Academy of Creative and Performing Arts, Leiden University.

Her academic research focuses on Indigenous Cinema and film making within and with communities. Her recent feature film In Times of Rain addresses the migration from rural mexico to the urban centres and was made in collaboration with both professional actors as well as Indigenous community members. The film combines a fictional narrative with a documentary approach. The project participated among others in the Raindance Co-production Forum 2015 and was selected for the Edinburgh International Film Festival Work in Progress section 2017. In Times of Rain recently won the award for Best Emerging Feature at the Oaxaca FilmFest and the award for Best Indigenous Feature Film at the RNIFF in Los Angeles.